![]() ![]() In January 2020, the company commenced a trial to analyse the initial clinical efficacy of MRx0518 plus preoperative radiotherapy to treat resectable pancreatic cancer. The company is collaborating on microbiome-based therapeutics to improve the efficacy of anti-cancer drugs such as Keytruda and Bavencio. In 4D pharma’s view, 2021’s surge of drug trials will continue and microbiome treatments will extend beyond gastrointestinal disorders. “We believe that our LBPs MRx0005 and MRx0029, which each have different mechanisms of action worthy of investigation, provide a unique opportunity to address the high unmet needs of those living with Parkinson’s disease.” 4D pharma is a world leader in the development of Live Biotherapeutics, a novel and emerging class of drugs, defined by the FDA as biological products that contain a live organism, such as a. The PAB is supported by Parkinson’s UK and offers 4D pharma a patient-centric perspective as it develops its new LBPs into clinical trials for treating neurodegenerative diseases such as Parkinson’s.ĤD pharma chief scientific officer Dr Alex Stevenson said: “We believe MRx0005 and MRx0029 are the first-ever Live Biotherapeutic products for Parkinson’s to enter the clinic. ![]() 4D pharma has developed a proprietary platform, MicroRx. MRx0029 was found to elicit dopaminergic neuronal phenotype differentiation in vitro and offer protection against dopaminergic neuron loss in the Parkinson’s disease animal model.ĤD pharma has formed a Patient Advisory Board (PAB) consisting of Parkinson’s patients in partnership with Parkinson’s UK. 4D pharma is a world leader in the development of Live Biotherapeutics, a novel and emerging class of drugs, defined by the FDA as biological products that contain a live organism, such as a bacterium, that is applicable to the prevention, treatment or cure of a disease. ![]()
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